Microbiology Immunology and Molecular Biology

The microbiology division focuses on development of indigenous microbial pesticides for mosquito control, characterization of the mosquitocidal compounds and development of formulations with varied residual activities. Pharmacologically important and commercially viable compounds from these mosquitocidal microbes have been identified, patented and commercialized. The post-graduate Public Health Entomology students of the institute are offered a course on Vector-Borne Parasites and Pathogens of Public Health Importance by the staff of this division.

 

The unit of Molecular biology and Immunology has been involved in research on the development of rapid surveillance tools including DNA/RNA based molecular tools; Ag-Ab based immunological tools; Electrochemical based biosensor for monitoring filarial transmission. Validation of the developed tools for assessing post MDA situation in the filariasis elimination programme at district level is carried out. In addition, a course on the application of molecular biology, Immunology and bioinformatics is conducted for the post-graduate Public Health Entomology students.

 

Surveillance laboratory:

The surveillance laboratory deals with detection of vector borne diseases. Molecular diagnostics based on reverse transcription polymerase chain reaction (RT-PCR) has been developed for Dengue, Japanese encephalitis & Zika viral detection. Scrub typhus fever caused by rickettsial bacteria, Orientia tsutsugamushiinfection from rodent/human blood samples is diagnosed by groEL gene and typing of O. tsutsugamushi strains is performed by sequencing immunodominant 56 kDa outer membrane protein (OMP) gene by nested PCR.

Last Updated on : 22/09/2016