Publications of Vector Control Center
Sadanandane, C, Mathew Nisha, P Jambulingam, and M Kalyanasundaram.
Abstract

Background & objectives : Repellents can play a useful role in reducing the man-vector contact and help in interrupting disease transmission. Never formulations are necessary to improve the efficacy of the repellent on the treated sites for enhanced protection.Methods: To determine the comparative efficacy, 20 per cent liposphere lotion formulation and 20 per cent alcohol solution of two insect insect repellents DEET and DEPA were evaluated for the extent of protection on rabbits against Aedes aegypti during the day in the laboratory and on human volunteers during the night against Culex quiniquefasciatus in the urban areas of Pondicherry, India. Results: In the laboratory the lotion formulations of DEPA and DEET were found to enhance the repellency by 1.5 (4.00 to 6.00 h) and 1.25 (4.00 to 5.00 h) times respectively compared to the alcohol sloution of the repellents against Ae.aegypti at the application rate of ).5 mg/cm2. In the field, the lotion formulation of DEPA at 0.3 mg/cm2 could increase the protection time from 6.30 to 8.36 h (1.3 times) whereas the lotion formulation of DEET at 0.3 mg/cm2 could increase the protection time from 6.54 to 8.42 h (1.2 times). Interpretation and conclusion: In laboratory nd field tests, the lotion formulations of both repellents were found to give a higher protection compared to alcohol solution. The lotion formulations of DEET and DEPA were found to be equally effective.

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Last Updated on:06/05/2014