Two mathematical models for the transmission of filariasis namely,



have been developed at VCRC in collaboration with the Parasite Epidemiology group of the Department of Zoology, Oxford University and the Centre for Decision Sciences on Tropical Diseas Control (CDTDC), Department of Public Health, Erasmus University Rotterdam respectively.


EPIFIL is a deterministic macro-simulation model, which simulates the dynamics of infection and disease at population level. The output of EPIFIL model includes age-specific infection prevalence, intensity of infection and chronic disease in humans. Epifil model can be used as a tool to decide the duration of control programme as well as appropriate control strategies to reach the target prevalence.


LYMFASIM is a stochastic microsimulation model which simulates the individual life histories of human and individual parasite. This model has been developed with a number of objectives in mind: Choice of control policy, prediction, planning, operational decision making, data analysis, evaluation, and surveillance,etc.


Both EPIFIL and LYMFASIM are validated based on epidemiological data collected by the VCRC in Pondicherry.


Last Updated on:06/05/2014